
Holiday rentals near Mayo Clinic Scottsdale
We found 3,802 holiday rentals — enter your dates for availability
Scroll through and discover holiday rentals close to Mayo Clinic Scottsdale that are perfect for your trip. Whether you're going on holiday with family or friends, holiday homes have the amenities that you expect for your stay, which might include a garden and Wi-Fi. You're sure to find a property to rent that has what everyone needs, including places that are non-smoking or accessible.
Holiday rentals with weekly discounts - Mayo Clinic Scottsdale
Showing deals for:14 Nov - 21 Nov
Image gallery for Fountain View, Heated Pool Included & A Family Retreat

1010 out of 10 rating
Exceptional
(11 reviews)
Fountain View, Heated Pool Included & A Family Retreat
Fountain Hills, AZ
8% off
Price is AU$10,315
AU$10,315
AU$1,474 per night
includes taxes & fees
Image gallery for Old Town Casa - Sip Splash Sun

1010 out of 10 rating
Exceptional
(5 reviews)
Old Town Casa - Sip Splash Sun
Scottsdale, AZ
8% off
Price is AU$4,558
AU$4,558
AU$651 per night
includes taxes & fees
Image gallery for Desert Luxury Retreat| Pool + Hot Tub | Dark Sky

9.89.8 out of 10 rating
Exceptional
(6 reviews)
Desert Luxury Retreat| Pool + Hot Tub | Dark Sky
Fountain Hills, AZ
7% off
Price is AU$6,230
AU$6,230
AU$890 per night
includes taxes & fees
Image gallery for BIGGEST BEST MANSION In NE Scottsdale Area- VIEWS, Infinity Pool, MOVIE THEATER!

1010 out of 10 rating
Exceptional
(12 reviews)
BIGGEST BEST MANSION In NE Scottsdale Area- VIEWS, Infinity Pool, MOVIE THEATER!
Fountain Hills, AZ
8% off
Price is AU$41,262
AU$41,262
AU$5,895 per night
includes taxes & fees
Image gallery for Spacious Scottsdale resort style home with pool and indoor/outdoor games

1010 out of 10 rating
Exceptional
(24 reviews)
Spacious Scottsdale resort style home with pool and indoor/outdoor games
Scottsdale, AZ
8% off
Price is AU$9,849
AU$9,849
AU$1,407 per night
includes taxes & fees
Image gallery for 5BR Luxury Stay: King Beds, Hot Tub, Games, Kids' Play Area & Private Pool

1010 out of 10 rating
Exceptional
(5 reviews)
5BR Luxury Stay: King Beds, Hot Tub, Games, Kids' Play Area & Private Pool
Scottsdale, AZ
12% off
Price is AU$10,796
AU$10,796
AU$1,542 per night
includes taxes & fees
Image gallery for Gorgeous 5 BR Oasis, Gated Pool, Putting Green, Fire Pit- perfect for families!

9.89.8 out of 10 rating
Exceptional
(67 reviews)
Gorgeous 5 BR Oasis, Gated Pool, Putting Green, Fire Pit- perfect for families!
Scottsdale, AZ
8% off
Price is AU$8,227
AU$8,227
AU$1,175 per night
includes taxes & fees
Image gallery for Stylish First-Floor Condo w/ Pool, Gym, Parking, King Bed & Trails + Pickleball

9.89.8 out of 10 rating
Exceptional
(19 reviews)
Stylish First-Floor Condo w/ Pool, Gym, Parking, King Bed & Trails + Pickleball
Scottsdale, AZ
8% off
Price is AU$3,190
AU$3,190
AU$456 per night
includes taxes & fees
Image gallery for Heated Pool, Lavish Yard! - The Desert Wanderer

9.69.6 out of 10 rating
Exceptional
(22 reviews)
Heated Pool, Lavish Yard! - The Desert Wanderer
Scottsdale, AZ
8% off
Price is AU$5,995
AU$5,995
AU$856 per night
includes taxes & fees
Image gallery for Entrepreneur's Enclave Private Pickleball w/ Heated Pool & Hot Tub

1010 out of 10 rating
Exceptional
(64 reviews)
Entrepreneur's Enclave Private Pickleball w/ Heated Pool & Hot Tub
Scottsdale, AZ
5% off
Price is AU$7,989
AU$7,989
AU$1,141 per night
includes taxes & fees
Image gallery for #SuiteHomeScottsdale: Your SPRING TRAINING BASECAMP in Old Town, Scottsdale!

9.89.8 out of 10 rating
Exceptional
(31 reviews)
#SuiteHomeScottsdale: Your SPRING TRAINING BASECAMP in Old Town, Scottsdale!
Scottsdale, AZ
8% off
Price is AU$4,445
AU$4,445
AU$635 per night
includes taxes & fees
Image gallery for Luxury Home/Heated Pool/Theater/ Putting Green AZ

1010 out of 10 rating
Exceptional
(13 reviews)
Luxury Home/Heated Pool/Theater/ Putting Green AZ
Mesa, AZ
7% off
Price is AU$6,896
AU$6,896
AU$985 per night
includes taxes & fees
Image gallery for Diving Pool, Family Friendly & Pet Friendly @Cozy Mesa home close to everything!

1010 out of 10 rating
Exceptional
(31 reviews)
Diving Pool, Family Friendly & Pet Friendly @Cozy Mesa home close to everything!
Mesa, AZ
8% off
Price is AU$3,598
AU$3,598
AU$514 per night
includes taxes & fees
Image gallery for Private guest house near TPC Golf, Car Shows, Spring Training, and hiking trails

1010 out of 10 rating
Exceptional
(49 reviews)
Private guest house near TPC Golf, Car Shows, Spring Training, and hiking trails
Scottsdale, AZ
8% off
Price is AU$2,477
AU$2,477
AU$354 per night
includes taxes & fees
Image gallery for Old Town Scottsdale Home with optional Heated Pool, Waterfalls, & Pool Table !

9.09.0 out of 10 rating
Wonderful
(39 reviews)
Old Town Scottsdale Home with optional Heated Pool, Waterfalls, & Pool Table !
Scottsdale, AZ
7% off
Price is AU$4,101
AU$4,101
AU$586 per night
includes taxes & fees
Image gallery for Spacious Scottsdale home with resort yard

1010 out of 10 rating
Exceptional
(22 reviews)
Spacious Scottsdale home with resort yard
Scottsdale, AZ
8% off
Price is AU$5,397
AU$5,397
AU$771 per night
includes taxes & fees
Image gallery for 10% off Aug/Sept! 4 BR/3 BA, NEW POOL/Hot Tub, perfect location near Old Town!!

1010 out of 10 rating
Exceptional
(64 reviews)
10% off Aug/Sept! 4 BR/3 BA, NEW POOL/Hot Tub, perfect location near Old Town!!
Scottsdale, AZ
8% off
Price is AU$5,456
AU$5,456
AU$779 per night
includes taxes & fees
Image gallery for 2025 VRBO Property of the Year: Scottsdale Luxury Estate: Pool, Spa & Pickleball

1010 out of 10 rating
Exceptional
(61 reviews)
2025 VRBO Property of the Year: Scottsdale Luxury Estate: Pool, Spa & Pickleball
Paradise Valley, AZ
8% off
Price is AU$21,460
AU$21,460
AU$3,066 per night
includes taxes & fees
Image gallery for "Scottsdale Area Oasis: Pool, Spa, Putting Green & Views!"

1010 out of 10 rating
Exceptional
(34 reviews)
"Scottsdale Area Oasis: Pool, Spa, Putting Green & Views!"
Fountain Hills, AZ
7% off
Price is AU$5,573
AU$5,573
AU$796 per night
includes taxes & fees
Image gallery for NEW Stylish Retreat near Old Town, Pool, FREE Hot Tub, Pet-Friendly!

1010 out of 10 rating
Exceptional
(14 reviews)
NEW Stylish Retreat near Old Town, Pool, FREE Hot Tub, Pet-Friendly!
Scottsdale, AZ
8% off
Price is AU$5,021
AU$5,021
AU$717 per night
includes taxes & fees
Image gallery for ScottsdaleResortVillas by AmericanVacationLiving

1010 out of 10 rating
Exceptional
(11 reviews)
ScottsdaleResortVillas by AmericanVacationLiving
Scottsdale, AZ
8% off
Price is AU$11,075
AU$11,075
AU$1,582 per night
includes taxes & fees
Image gallery for Glamorous Renovated Desert Oasis, Heated Pool, Tub

8.68.6 out of 10 rating
Excellent
(7 reviews)
Glamorous Renovated Desert Oasis, Heated Pool, Tub
Scottsdale, AZ
20% off
Price is AU$6,212
AU$6,212
AU$887 per night
includes taxes & fees
Image gallery for New heated resort pool , jacuzzi, out door sound system, secluded courtyard.<br>

9.89.8 out of 10 rating
Exceptional
(52 reviews)
New heated resort pool , jacuzzi, out door sound system, secluded courtyard.<br>
Scottsdale, AZ
7% off
Price is AU$10,016
AU$10,016
AU$1,431 per night
includes taxes & fees
Image gallery for Winter getaway, come escape with a pool!

1010 out of 10 rating
Exceptional
(21 reviews)
Winter getaway, come escape with a pool!
Fountain Hills, AZ
7% off
Price is AU$3,161
AU$3,161
AU$452 per night
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - Mayo Clinic Scottsdale
Ground Floor Poolside Condo! Mayo Clinic Shea Super Close!
Sleeps 4 · 2 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
22 reviews(22 reviews)
Luxe Scottsdale Condo - Newly Refurbished Ground Floor Unit!
Sleeps 4 · 2 bedrooms · 2 bathrooms
1010 out of 10
Exceptionalexceptional
Clean & Bright 2BR/2BA Scottsdale Vacation Rental - Your Perfect Getaway!
Sleeps 4 · 2 bedrooms · 2 bathrooms
1010 out of 10
Exceptionalexceptional
80 reviews(80 reviews)
Your Perfect Scottsdale Home Base Near Mayo Clinic Campus! Free Shuttle Service!
Sleeps 2 · 1 bedroom · 1 bathroom
9.69.6 out of 10
Exceptionalexceptional
7 reviews(7 reviews)
Luxury designer condo!
Sleeps 6 · 1 bedroom · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
23 reviews(23 reviews)
Meridian CondoResorts
Sleeps 13 · 6 bedrooms
8.68.6 out of 10
Excellentexcellent
854 reviews(854 reviews)
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, laundry, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value