
Holiday rentals near Sioux Empire Medical Museum
We found 239 holiday rentals — enter your dates for availability
Take a look at holiday rentals near Sioux Empire Medical Museum that provide the perfect home base for your trip. Whether you're travelling with your children and pets, with friends or just your children, holiday homes have the best amenities for spending time at your holiday home, which might include a garden and pool. Whatever you're looking for, you'll be able to choose a property to rent for everyone's needs, including accessible or non-smoking choices.
Holiday rentals with weekly discounts - Sioux Empire Medical Museum
Showing deals for:3 Oct - 10 Oct
Image gallery for 4-bedroom vacation home: Sleeps 12, 2 miles to DT & Premier Center

8.88.8 out of 10 rating
Excellent
(17 reviews)
4-bedroom vacation home: Sleeps 12, 2 miles to DT & Premier Center
Sioux Falls, SD
8% off
Price is AU$2,618
AU$2,618
AU$374 per night
includes taxes & fees
Image gallery for A Ray of Sunshine- A 2 Bedroom Home near The Denny, Downtown, and I-29

9.69.6 out of 10 rating
Exceptional
(52 reviews)
A Ray of Sunshine- A 2 Bedroom Home near The Denny, Downtown, and I-29
Sioux Falls, SD
8% off
Price is AU$1,749
AU$1,749
AU$250 per night
includes taxes & fees
Image gallery for Retro Haven - mid-century modern styling - 4 bedrooms, 2.5 baths,

1010 out of 10 rating
Exceptional
(56 reviews)
Retro Haven - mid-century modern styling - 4 bedrooms, 2.5 baths,
Sioux Falls, SD
8% off
Price is AU$2,734
AU$2,734
AU$391 per night
includes taxes & fees
Image gallery for Cozy Copper Cabin in the City - the whole place is yours!

9.89.8 out of 10 rating
Exceptional
(17 reviews)
Cozy Copper Cabin in the City - the whole place is yours!
Sioux Falls, SD
15% off
Price is AU$2,749
AU$2,749
AU$393 per night
includes taxes & fees
Image gallery for Brick House

1010 out of 10 rating
Exceptional
(6 reviews)
Brick House
Sioux Falls, SD
8% off
Price is AU$2,232
AU$2,232
AU$319 per night
includes taxes & fees
Image gallery for Relaxing Townhouse Getaway with great location in Sioux Falls.

1010 out of 10 rating
Exceptional
(17 reviews)
Relaxing Townhouse Getaway with great location in Sioux Falls.
Sioux Falls, SD
7% off
Price is AU$1,878
AU$1,878
AU$268 per night
includes taxes & fees
Image gallery for Sojourners Cozy Retreat-Heart of SF-4bd | 2 ba

1010 out of 10 rating
Exceptional
(18 reviews)
Sojourners Cozy Retreat-Heart of SF-4bd | 2 ba
Sioux Falls, SD
17% off
Price is AU$4,887
AU$4,887
AU$698 per night
includes taxes & fees
Image gallery for East side single family home near Harmadon ball fields

1010 out of 10 rating
Exceptional
(26 reviews)
East side single family home near Harmadon ball fields
Sioux Falls, SD
8% off
Price is AU$2,923
AU$2,923
AU$418 per night
includes taxes & fees
Image gallery for Lakeside Getaway Just West of Sioux Falls

9.89.8 out of 10 rating
Exceptional
(30 reviews)
Lakeside Getaway Just West of Sioux Falls
Hartford, SD
8% off
Price is AU$2,613
AU$2,613
AU$373 per night
includes taxes & fees
Image gallery for Comfort, friendly, low crime, close to parks, hospitals, shopping

9.69.6 out of 10 rating
Exceptional
(5 reviews)
Comfort, friendly, low crime, close to parks, hospitals, shopping
Sioux Falls, SD
15% off
Price is AU$1,969
AU$1,969
AU$281 per night
includes taxes & fees
Image gallery for Relaxing 2 Bed 2 Bath with Garage!

1010 out of 10 rating
Exceptional
(72 reviews)
Relaxing 2 Bed 2 Bath with Garage!
Sioux Falls, SD
9% off
Price is AU$1,869
AU$1,869
AU$267 per night
includes taxes & fees
Image gallery for Oasis Outside Downtown

9.69.6 out of 10 rating
Exceptional
(5 reviews)
Oasis Outside Downtown
Sioux Falls, SD
8% off
Price is AU$2,884
AU$2,884
AU$412 per night
includes taxes & fees
Image gallery for Benelo | Midcentury Modern Single-Level Home, 3 BR

1010 out of 10 rating
Exceptional
(25 reviews)
Benelo | Midcentury Modern Single-Level Home, 3 BR
Sioux Falls, SD
8% off
Price is AU$2,961
AU$2,961
AU$423 per night
includes taxes & fees
Image gallery for 4-bedroom vacation home: Sleeps 13. Foosball, 65" TV, Golf, 4 Season Room

1010 out of 10 rating
Exceptional
(92 reviews)
4-bedroom vacation home: Sleeps 13. Foosball, 65" TV, Golf, 4 Season Room
Sioux Falls, SD
8% off
Price is AU$3,500
AU$3,500
AU$500 per night
includes taxes & fees
Image gallery for Charming 2+ bedroom house in walking distance from Sanford, Augi, & U of S.F.

1010 out of 10 rating
Exceptional
(11 reviews)
Charming 2+ bedroom house in walking distance from Sanford, Augi, & U of S.F.
Sioux Falls, SD
8% off
Price is AU$1,570
AU$1,570
AU$224 per night
includes taxes & fees
Image gallery for Wonderful Home in Central Sioux Falls

9.89.8 out of 10 rating
Exceptional
(74 reviews)
Wonderful Home in Central Sioux Falls
Sioux Falls, South Dakota
8% off
Price is AU$1,855
AU$1,855
AU$265 per night
includes taxes & fees
Image gallery for Aspen Villa-Country Club, Augustana, USF & Sanford Med.

1010 out of 10 rating
Exceptional
(31 reviews)
Aspen Villa-Country Club, Augustana, USF & Sanford Med.
Sioux Falls, SD
8% off
Price is AU$3,139
AU$3,139
AU$448 per night
includes taxes & fees
Image gallery for 3-BR vacation home w/ large entertaining areas: Sleeps 11, 5 miles to Falls Park

9.69.6 out of 10 rating
Exceptional
(20 reviews)
3-BR vacation home w/ large entertaining areas: Sleeps 11, 5 miles to Falls Park
Sioux Falls, SD
8% off
Price is AU$2,941
AU$2,941
AU$420 per night
includes taxes & fees
Image gallery for Mid-Century Spacious Ranch

1010 out of 10 rating
Exceptional
(5 reviews)
Mid-Century Spacious Ranch
Sioux Falls, SD
8% off
Price is AU$3,505
AU$3,505
AU$501 per night
includes taxes & fees
Image gallery for Grand Palace

1010 out of 10 rating
Exceptional
(13 reviews)
Grand Palace
Sioux Falls, SD
8% off
Price is AU$4,023
AU$4,023
AU$575 per night
includes taxes & fees
Image gallery for House By Sanford Sports Complex - Family Friendly

9.49.4 out of 10 rating
Exceptional
(23 reviews)
House By Sanford Sports Complex - Family Friendly
Sioux Falls, SD
8% off
Price is AU$2,469
AU$2,469
AU$353 per night
includes taxes & fees
Image gallery for The Firehouse: 3 bed, central location, historic

9.89.8 out of 10 rating
Exceptional
(14 reviews)
The Firehouse: 3 bed, central location, historic
Sioux Falls, SD
8% off
Price is AU$2,213
AU$2,213
AU$316 per night
includes taxes & fees
Image gallery for 2-bedroom vacation home; 1 mile from DT: Hot Tub, 86" TV, Golf, + Fenced Yard

1010 out of 10 rating
Exceptional
(87 reviews)
2-bedroom vacation home; 1 mile from DT: Hot Tub, 86" TV, Golf, + Fenced Yard
Sioux Falls, SD
8% off
Price is AU$2,229
AU$2,229
AU$318 per night
includes taxes & fees
Image gallery for Fully Furnished 3 Bedroom - 2 Bath - Double Garage

1010 out of 10 rating
Exceptional
(145 reviews)
Fully Furnished 3 Bedroom - 2 Bath - Double Garage
Sioux Falls, SD
8% off
Price is AU$1,869
AU$1,869
AU$267 per night
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - Sioux Empire Medical Museum
2-bedroom vacation home; 1 mile from DT: Hot Tub, 86" TV, Golf, + Fenced Yard
Sleeps 6 · 2 bedrooms · 1 bathroom
1010 out of 10
Exceptionalexceptional
87 reviews(87 reviews)
Hilltop Firecracker- a 2 Bedroom Homestead near The Denny & Downtown Sioux Falls
Sleeps 7 · 2 bedrooms · 1 bathroom
8.68.6 out of 10
Excellentexcellent
4 reviews(4 reviews)
4-bedroom vacation home: Sleeps 13. Foosball, 65" TV, Golf, 4 Season Room
Sleeps 11 · 4 bedrooms · 2+ bathrooms
1010 out of 10
Exceptionalexceptional
92 reviews(92 reviews)
3-BR vacation home w/ large entertaining areas: Sleeps 11, 5 miles to Falls Park
Sleeps 12 · 3 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
20 reviews(20 reviews)
Pond View Retreat, 6 Bedroom, 4 Bath, 3 Level Luxury Home In Sioux Falls.
Sleeps 10 · 6 bedrooms · 3+ bathrooms
1010 out of 10
Exceptionalexceptional
6 reviews(6 reviews)
McKennan Park Poolside Oasis
Sleeps 10 · 4 bedrooms · 2+ bathrooms
9.29.2 out of 10
Wonderfulwonderful
39 reviews(39 reviews)
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, laundry, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value