A panoramic view of a historic city with a river, prominent domed buildings, and a bridge.

Florence house rentals

We found 49 house rentals — enter your dates for availability

Explore Florence house rentals

Image of Come Stay A While

Come Stay A While

Sleeps 6 · 3 bedrooms · 1 bathroom

Image of Florence Home

Florence Home

Sleeps 6 · 3 bedrooms · 1+ bathroom

Image of Walking distance from one of South Carolina's top Medical centers.

Premier Host

Walking distance from one of South Carolina's top Medical centers.

Sleeps 6 · 3 bedrooms · 2 bathrooms

Image of Serene 3-bedroom house with near downtown Florence

Serene 3-bedroom house with near downtown Florence

Sleeps 10 · 3 bedrooms · 2 bathrooms

Image of Pickle in the Park - 1 Bedroom Studio Apartment

Pickle in the Park - 1 Bedroom Studio Apartment

Sleeps 2 · 1 bedroom · 1 bathroom

Image of Collins Quarters - Full House in the heart of Florence!

Collins Quarters - Full House in the heart of Florence!

Sleeps 6 · 2 bedrooms · 2+ bathrooms

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