A dense cluster of vibrant pink azaleas in full bloom.

Semmes house rentals

We found 132 house rentals — enter your dates for availability

Explore Semmes house rentals

Image of Spacious 4 bedroom/2 bath in Sweet Home Alabama

Spacious 4 bedroom/2 bath in Sweet Home Alabama

Sleeps 8 · 4 bedrooms · 2 bathrooms

Image of Dog-Friendly Alabama Retreat w/ Patio & Fire Pit!

Premier Host

Dog-Friendly Alabama Retreat w/ Patio & Fire Pit!

Sleeps 6 · 3 bedrooms · 2 bathrooms

Image of Oak Hill- 2 Acres with Pool, 4 Bedrooms

Premier Host

Oak Hill- 2 Acres with Pool, 4 Bedrooms

Sleeps 10 · 4 bedrooms · 2 bathrooms

Image of Penny Lake Palace

Penny Lake Palace

Sleeps 8 · 3 bedrooms · 3 bathrooms

Image of Enchanting Forestwood Retreat

Enchanting Forestwood Retreat

Sleeps 12 · 3 bedrooms · 2 bathrooms

Image of Cozy Casa on the Hill-Mins to South Campus, RTJ Golf, Tennis Courts, I-65

Cozy Casa on the Hill-Mins to South Campus, RTJ Golf, Tennis Courts, I-65

Sleeps 8 · 3 bedrooms · 2+ bathrooms

Find spaces that suit your style

House

Condo/Apartment

Cabin

Cottage

Villa

Chalet

Peace of mind
Our Book with Confidence Guarantee gives you 24/7 support
More quality time
From booking to staying, the whole process is simple and enjoyable
All the privacy of home
Enjoy full kitchens, laundry, pools, gardens and more
More for less
More space, more privacy, more amenities — more value