Photo by Michele Butts

La Mesa house rentals

We found 3,075 house rentals — enter your dates for availability

Find spaces that suit your style

  • Peace of mind

    Our Book with Confidence Guarantee gives you 24/7 support

  • More quality time

    From booking to staying, the whole process is simple and enjoyable

  • All the privacy of home

    Enjoy full kitchens, laundry, pools, gardens and more

  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Are there any holiday home rentals in La Mesa?
Select one of our 3,075 holiday home rentals in La Mesa and you'll have the perfect base for your next travel adventure. Windsor Hills, Rolando Village and Grossmont are some of the city's best areas to stay.
How much does it cost to stay in a holiday rental house in La Mesa?
Your picture-perfect holiday home rental in La Mesa awaits on Stayz, with a range of prices from wallet-friendly accommodation to more exclusive properties. Enter your trip details to filter your search, making sure you find the best place that everyone will love.
When is the best time to rent a holiday house in La Mesa?
It can all depend on the type of weather you enjoy, among other factors. Many people visiting East County book a La Mesa holiday home rental in May, when the average temperature ranges from 13ÂşC to 22ÂşC.
Where can I rent a La Mesa holiday house with great views?
Stayz makes it easy to find the stunning views you're looking for in your holiday house. Just use our "Location" filter to narrow down the kind of area you'd prefer to stay in, and the views you want to stare out at, while searching holiday home rentals in La Mesa.
Does La Mesa have any weekend house rentals?
Explore our weekend rentals and get packing for a thrilling couple of days away. Our tips for booking your ideal house in La Mesa? Be flexible when searching and change your dates until you find the holiday home rental that matches your needs.
Are there any pet-friendly house rentals in La Mesa?
Spend your next adventure with your furry friend at one of our five pet-friendly holiday home rentals in La Mesa. These stays come with perks that'll make your pup feel welcome, including a backyard to play in. Just select the "Pets allowed" filter to book a house that has room for every beloved member of your family.
What are the top things to do in La Mesa?
It's easy to see why families love La Mesa, with cool attractions like San Diego Zoo, Balboa Park and Petco Park to explore. Discover this destination's wonders together and then return to the cosy comforts of your holiday home rental.
Why should I book my holiday rental house with Stayz?
First-rate customer support from the moment you book until after your stay is among the many reasons to choose us for your upcoming holiday home rental. We also have properties that go beyond the conventional hotel room — think houses in stunning locations, whether that's by the ocean or in the countryside. And with flexible cancellation policies and benefits like payment protection, we make getting away easy.
Houses in La Mesa
Houses in Windsor Hills