Santo Spirito holiday rentals

We found 1,246 holiday rentals — enter your dates for availability

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October 2025

November 2025

Discover a selection of 14 homes, 404 apartments and other holiday rentals in Santo Spirito that are perfect for your trip. Whether you're travelling with family, friends or just your furry companion, holiday homes have the amenities that you expect for your stay, which might include Wi-Fi and a washer and dryer. At the end of the day, you'll find a property to rent for everyone's needs, including a place that is accessible or non-smoking.

Holiday rentals with weekly discounts - Santo Spirito

Showing deals for:26 Dec - 2 Jan

Exceptional

(5 reviews)

Rare exclusive loft in Florence

Florence, Firenze

9% off

for 7 nights, 1 apartment

AU$838 per night

includes taxes & fees

Exceptional

(5 reviews)

Luxury Palazzo Tempi Apartment - Historical Center, Florence

Florence, Città Metropolitana di Firenze

9% off

for 7 nights, 1 apartment

AU$1,374 per night

includes taxes & fees

Exceptional

(203 reviews)

Amazing Views of Ponte Vecchio and Uffizi - Extremely silent - Modern - WiFi

Florence, Toscana

13% off

for 7 nights, 1 apartment

AU$435 per night

includes taxes & fees

Exceptional

(195 reviews)

Typical Florentine dwelling within the walls of the city near the Boboli Gardens, Pitti Palace and Ponte Vecchio

Florence, Tuscany

8% off

for 7 nights, 1 apartment

AU$497 per night

includes taxes & fees

The CANAPY bedroom with the canapy bed and the balcony on the garden area

Exceptional

(59 reviews)

Beautiful Apartment in the Historic City Centre of Florence

Florence, Toscana

8% off

for 7 nights, 1 apartment

AU$363 per night

includes taxes & fees

Exceptional

(42 reviews)

THE BEST RELATION BETWEEN QUALITY 'PRICE AND HAPPINESS'.

Florence, FI

8% off

for 7 nights, 1 apartment

AU$445 per night

includes taxes & fees

Exceptional

(30 reviews)

Florence View Luxury Apartment just steps from Ponte Vecchio

Florence, Toscana

6% off

for 7 nights, 1 apartment

AU$726 per night

includes taxes & fees

Exceptional

(207 reviews)

"Renaissance Retreat" by WP Relais , Palazzo Uguccioni, in Piazza della Signoria

Florence, Toscana

9% off

for 7 nights, 1 apartment

AU$1,172 per night

includes taxes & fees

Exceptional

(142 reviews)

TWO BEDROOM LOFT NEAR PONTE VECCHIO/OLD BRIDGE WITH FREE BREAKFAST ITEMS OFFERED

Florence, Toscana

8% off

for 7 nights, 1 apartment

AU$622 per night

includes taxes & fees

Exceptional

(42 reviews)

Loft apartment by WP Relais in the 17th-century Palazzo Berardi

Florence, Tuscany

9% off

for 7 nights, 1 apartment

AU$917 per night

includes taxes & fees

Exceptional

(8 reviews)

Love Honeymoon Apartment Piazza Signoria View WiFi AC

Florence, Tuscany

9% off

for 7 nights, 1 apartment

AU$426 per night

includes taxes & fees

Exceptional

(49 reviews)

Charming apartment in the heart of the historic center of Florence

Florence, Toscana Italia

5% off

for 7 nights, 1 apartment

AU$395 per night

includes taxes & fees

Find spaces that suit your style

House

Condo/Apartment

Find properties near top attractions in Santo Spirito

Piazza Santo Spirito

Find the best place to stay - Santo Spirito

Premier Host

Charming Two Bedroom Apartment in the Heart of San Frediano: Exposed Beams and Chic Atmosphere

Sleeps 4 · 1 bedroom

Top rated rentals - Santo Spirito

Premier Host

Family Holiday in Florence

We are a family of 5 (2 Adults, 3 Teenagers) and stayed 4 nights in Sonia’s apartment. What a wonderful experience! Sonia was there at checkin and went through all the things to do with the apartment in great detail. She also recommended many great local restaurants and things to do around Florence.The apartment itself was very clean and configured to 3 bedrooms and the 2nd bathroom made the stay very comfortable for our family of 5. The outdoor courtyard is also available, but we didn’t use it much as it was winter and cold.The apartment is very quiet and the location is close enough to walk easily into town and all the main attractions. The bus is also just outside the apartment.Overall, a great place to stay in a quiet neighbourhood and would definitely stay again when in Florence. Thank you Sonia for your hospitality!

Oscar L.

Stayed Dec 2024

Premier Host

Granny’s 70th

Our apartment was fabulous, the whole experience was 1st class. To the checking in with Maria, our door man Stefano and the location. The apartment was beautifully presented had everything to make our stay very comfortable. We could walk everywhere with great restaurants, close to a grocery store down the road with everything we needed. Stephano our doorman was always very helpful giving us places to see and places to eat. He was also very helpful calling us a taxi with all our luggage to get to the train station. Thank you for our wonderful stay and will recommend to everyone.

Sharon M.

Stayed Jan 2023

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Frequently asked questions

What is the most popular type of holiday home accommodation in Santo Spirito?

Based on our research, apartments are the most in-demand type of holiday property in Santo Spirito. But as you might expect, everyone's idea of the perfect trip can vary. Stayz has holiday homes of all shapes and sizes, so you're sure to discover the best fit for your needs.

How much does it cost to rent a holiday home in Santo Spirito?

The average price for a holiday home in Santo Spirito can vary based on factors like length of stay, season and property type. Whether you're dreaming about a villa with space for extended family or a quaint cottage for just you and the kids, just add your travel dates to discover stays with amazing value.

How much does it cost to rent a beach house in Santo Spirito?

The average price for a holiday home close to the beach in Santo Spirito depends on when you'll be there and the type and size of property you want. You can easily find prices on Stayz by entering your destination and travel dates. Then use our filter tool to choose the number of bedrooms and amenities that you prefer, such as WiFi, air conditioning and a hot tub.

Are there pet-friendly holiday homes in Santo Spirito?

Yes, there are. You'll have your pick of 417 holiday homes that cater to pets in Santo Spirito. Lots of our pet-friendly holiday homes even have an area outdoors for your fur child to play around in, special dog beds, complimentary treats and proximity to parks and green space. Apply the "Pets allowed" filter to find a holiday home on Stayz that's pawfect.

Can I rent a house with a pool in Santo Spirito?

Add a new level of fun to your holiday by staying in one of the two houses with a private pool in Santo Spirito. Use our search filter to find properties with pools on Stayz, then spend carefree days splishing and splashing in a swimming pool that's all your own.

What are popular home amenities in Santo Spirito?

A barbecue grill, a swimming pool and tennis rank as the most popular home amenities in Santo Spirito. Whether you're heading away on your own, with your spouse or a group of family members, Stayz will help you find a holiday home that suits your tastes with a load of extras you'll love.

Are there large group holiday homes in Santo Spirito?

You'll find 12 holiday homes in Santo Spirito that can sleep 10 or more people. Whether you're organising a trip with extended family or a special event like a birthday party, there's enough room to get your favourite people together under one roof.

Are there holiday homes in Santo Spirito that welcome kids?

Gather the whole crew for fun-filled adventures in Santo Spirito at one of our 413 family-friendly properties. Lots of these stays feature conveniences that are ideal for getaways with children, including dining rooms, bunk beds and patios. Just check the "Properties good for families" filter box and decide on your favourite.

Are there one-bedroom holiday homes in Santo Spirito?

Yes, you can choose from 187 one-bedroom homes in Santo Spirito. Whether you'd like a cosy cottage or a cabin, our one-bedroom properties are great if you don't need loads of space. One of the perks of having your own pad? You won't need to share your trip with strangers.

Can I find two-bedroom holiday homes in Santo Spirito?

Gather your loved ones and experience complete comfort and privacy in one of the 135 two-bedroom holiday homes Santo Spirito has to offer.

Are there holiday homes with WiFi in Santo Spirito?

Santo Spirito has 113 holiday homes with WiFi, so you'll be able to stay connected during your trip. Simply check the "WiFi" box in our handy search filter for a list of properties with this feature. From streaming movie blockbusters to sending emails, these Stayz homes make it a cinch to go online.

How can I find holiday homes with air conditioning in Santo Spirito?

You'll have a choice of 363 holiday homes with air conditioning in Santo Spirito providing that cool, cool breeze and extra comfort level. Just enter your desired travel dates and then use our filter tool to help you find stays with air conditioning.

How old do you have to be to rent a holiday home in Santo Spirito?

The minimum age requirements can vary across properties on Stayz, so double-check the rules of the holiday home in Santo Spirito you want to book. But in general, it's 16, 18 or 21.

How long can I rent a holiday home in Santo Spirito for?

The length of time you can book a holiday home in Santo Spirito depends on the property. Just enter your selected dates to view a list of options offering extended stays. With loads of creature comforts like laundries and air conditioning, as well as some offering weekly or monthly discounted prices, you're sure to discover somewhere perfect to call your home away from home in Santo Spirito.

Santo Spirito holiday rentals

Holiday rentals with weekly discounts - Santo Spirito

Image gallery for Rare exclusive loft in Florence

Rare exclusive loft in Florence

Find spaces that suit your style

Find properties near top attractions in Santo Spirito

Map Attractions

Piazza Santo Spirito

Find the best place to stay - Santo Spirito

Charming Two Bedroom Apartment in the Heart of San Frediano: Exposed Beams and Chic Atmosphere

Top rated rentals - Santo Spirito

Family Holiday in Florence

Peace of mind

More quality time

All the privacy of home

More for less

Frequently asked questions

Holiday Rental options in Santo Spirito

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