Top Santo Spirito, ITA house rentals

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Cozy and modern studio apartment by Mmega

Sleeps 4 · 1 bedroom · 1 bathroom

Premier Host

Once Upon A Time in Florence: NEW LUXURY AND CHARMING SUITE PONTE VECCHIO

Sleeps 6 · 3 bedrooms · 2 bathrooms

Top rated house rentals - Santo Spirito

Premier Host

Excellent place right next to Ponte Vecchio

We greatly enjoyed our stay here. Martina was very organised in contacting us before we checked in and then left excellent guides in the apartment for a 2 day stay. The property is clean, well equipped and extremely well located. We had a great time.

Michael H.

Stayed Apr 2025

Florentine Dream

We have been travelling the world for over 2 years now & my husband & adult son agreed this was the BEST ‘home away from home’ stay we've found so far!! Its simply gorgeous, was immaculately clean, designed with thought & intention and Ginevra even left treats for us!! Adored the pink couches, green bathroom and beautiful books!! The apartment is located in a lovely leafy suburb just out of town & has loads of cute cafes nearby!! I would highly recommend staying here!!

Andrea T.

Stayed Sept 2024

Premier Host

A truely magical stay

What a wonderful experience. The location is extraordinary but to focus solely on the location is selling this apartment short. The presentation of the apartment in this 16th century building was everything we had hoped for. The host, Lorenzo, was so welcoming and generous, nothing was too much trouble. A bottle of wine on arrival, so beautifully presented, was the perfect start to our stay. A lift meant we didn’t have to lug our suitcases up multiple flights of stairs. And then there is the location! Beware though, being opposite Florence’s famous leather market might result in some damage to your wallet! Thank you Lorenzo for a truely memorable stay.

Stephen M.

Stayed Jan 2024

Premier Host

Fantastic apartment

Lovely apartment, comfortable, well equipped, fantastic location. Michele went above and beyond to make our stay a great one.

Andrea H.

Stayed Jan 2023

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Frequently asked questions

Are there any holiday home homes in Santo Spirito?

Take your pick of 24 holiday home homes in Santo Spirito. With interesting attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery on your doorstep, this is a great neighbourhood to stay in.

How much does it cost to stay in a holiday home house in Santo Spirito?

Your picture-perfect holiday home home in Santo Spirito is waiting to be discovered, with a range of prices from budget-friendly accommodation to more luxurious properties. Enter your travel dates and then filter based on your preferences, ensuring you find the right place that everyone will love.

When is the best time to rent a holiday house in Santo Spirito?

The best time depends on individual preferences. July is the most popular time of year to stay in a Santo Spirito holiday home home, but if you want to avoid the crowds, consider travelling outside of peak season.

Where can I rent a Santo Spirito holiday house with great views?

When looking for your holiday home home in Santo Spirito, take advantage of our "Location" filter. This will help you choose the sorts of areas you want to stay in, whether that's near nature or somewhere more central.

Does Santo Spirito have any weekend house homes?

Explore our weekend homes and get packing for a memorable few days away. Our tips for booking the ideal house in Santo Spirito? Stay flexible when searching and change your dates until you find the holiday home home that suits your needs.

Are there any pet-friendly house homes in Santo Spirito?

Share your next adventure with your furry companion at one of the 22 pet-friendly holiday home homes in Santo Spirito. These stays come with features that'll make your pup feel at home, such as a fenced-in yard to play in. Just check the "Pets allowed" filter to find a house that has space for every precious member of your family.

What are the top things to do in Santo Spirito?

At Stayz, we're all about helping you have fun family adventures, so check out top attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Discover the perfect holiday home home in Santo Spirito that puts you near all these major sights and more.